EAN: 9781493932733

ELECTROPHYSIOLOGICAL ANALYSIS OF SYNAPTIC TRANS...

Electrophysiological methods are used at nearly all levels of biological research today. From
basic science investigation to bringing new drugs to market  electrophysiology is an
indispensable research technique that provides essential insights into cellular and molecular
functions. This work is intended to be a practical guide for understanding and using
contemporary electrophysiological manipulations and assays in brain research. New researchers
attempting to learn electrophysiological techniques are confronted with a lack of adequate
guiding resources. Currently  most electrophysiology-based research knowledge is passed on by
experienced individuals to others within the same laboratory. But  this master-apprentice
scenario has many inherent difficulties  as it is both a time intensive process and also leads
to incomplete knowledge transfer  or even superstitious and maladaptive practices. Few external
guiding resources exist for a budding researcher who wishes to gain the skills necessary to
conduct responsible and competent electrophysiology research. Dr. Yan Dong  an expert in
utilizing electrophysiological techniques for brain research with fifteen years of experience 
and Peter Neumann hope this work can act as a concise and practical aid to remedy the current
situation. This book will cover both basic methods and advanced techniques clearly and in depth
as well as the essential background and theory necessary to understand the methods.
Additionally  this book also covers conventional and contemporary patch-clamp methods 
experimental design  data collection and analysis  common pitfalls to avoid  important nuances
technical concerns  practical applications  and advice for teaching new researchers. Together 
this represents a contemporary best-practices guide for collecting and interpreting
electrophysiological data for brain research. ¿

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