Thisbook constitutes the proceedings of the 20th Annual Conference on Research inComputational
Molecular Biology RECOMB 2016 held in Santa Monica CA USA inApril 2016. The 15 regular
papers presented in this volume were carefullyreviewed and selected from 172 submissions. 20
short abstracts are included inthe back matter of the volume. They report on original research
in all areas ofcomputational molecular biology and bioinformatics.
