EAN: 9783863597153

APPLIED MICROBIOLOGY MULTI-SCALE MODELING IN ...

Drug-induced toxicity is a major concern in drug development and clinical care. Methods
translating in vitro findings into the patient level are needed. This work presents
computational concepts to estimate the impact of drug exposure on the cellular biochemistry
that are ultimately driving drug-induced toxicities. Thus  contributing to our mechanistic
understanding of the underlying processes and may allow the identification of biomarkers that
indicate drug efficacy and toxicity in the future.

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