This book contains 14 original review chapters each yielding new exciting and intriguing data
about the emerging understanding of nucleolar structure and function in normal stressed and
diseased cells. The goal of this work is to provide special insight into the nucleolus of the
past present and future as well its regulation translocation and biomedical function. A
multitude of topics are introduced and discussed in detail including nucleologenesis
nucleolar architecture nucleolar targeting retention anchoring translocation and the
relationship between the nucleolus and cancer. This book also brings together work from several
different species from human to Drosophila to Dictyostelium and other eukaryotic microbes. The
final chapter summarizes some of the issues brought up in the various chapters with a view to
future research. This book supports the continued emergence of the nucleolus as a dynamic
intranuclear region that oversees a vast diversity of events.
