Neuropsychiatric Disorders and Epigenetics is a comprehensive reference for the epigenetic
basis of most common neuropsychiatric disorders. The volume is organized into chapters
representing individual neuropsychiatric disorders from addition to obesity contributed by
leading experts in their respective fields. The epigenetic aspects of each disorder are
discussed in the context of the full range of epigenetic mechanisms including DNA modification
histone post-translational modification chromatin organization and non-coding RNA. A
particular emphasis is placed on potential epigenetic interventions when the effects of
environmental stimuli on epigenetic states is particularly relevant o disease. Recent
discoveries in epigenetic research enabled by epic advances in genomic technologies have
positioned the field for broad translation to therapeutic interventions for previously
unmanageable disorders Neuropsychiatric disorders represent a prime target of epigenetic
interventions as they are highly debilitating often chronic diseases with enormous costs to
society. Thus this volume will help define epigenetics as a key player in neuropsychiatric
disorders highlighting the full spectrum of epigenetic mechanisms underlying such disorders
and introducing the vast range of epigenetic therapies under development.
