Handbook of Neuroemergency Clinical Trials Second Edition focuses on the practice of clinical
trials in acute neuroscience populations or what have been called neuroemergencies.
Neuroemergencies are complex life-threatening diseases and disorders often with devastating
consequences including death or disability. The overall costs are staggering in terms of
annual incidence and costs associated with treatment and survival yet despite their
significance as public health issues there are few drugs and devices available for definitive
treatment. The book focuses on novel therapies and the unique challenges their intended targets
pose for the design and analysis of clinical trials. This volume provides neurologists
neuroscientists and drug developers with a more complete understanding of the scientific and
medical issues of relevance in designing and initiating clinical development plans for novel
drugs intended for acute neuroscience populations. The editors provide the best understanding
of the pitfalls associated with acute CNS drug development and the best information on how to
approach and solve issues that have plagued drug development.
