Cardiac Cellular Electrophysiology is intended for the clinical cardiologist who wishes to
refresh or deepen his understanding of the cellular basis of cardiac electrophysiology for
researchers interested in the basis of the electrical activity of the heart such as clinical
investigators physiologists or pharmacologists for teachers in physiology pharmacology and
other biomedical studies and for medical students from graduate to postgraduate level. Cardiac
Cellular Electrophysiology starts with a primer of basic electrophysiology the cardiac action
potential and the physiological basis of the electrocardiogram. Our second aim after having
introduced the basic concepts was to continue with giving an overview of the properties of the
most important ionic currents in the heart and to treat their modulation in order to deal
with the mechanisms underlying cardiac ischaemia arrhythmias and remodelling. Edward Carmeliet
and Johan Vereecke Katholieke University Leuven Belgium have collaborated for over 30 years
in cardiac electrophysiology research. Their studies include the genesis of the normal action
potential its changes in ischaemia the effect of drugs and the mechanism of arrhythmias
using techniques from the classic potential registration with intracellular microelectrodes to
whole cell clamp and single channel measurements.
