EAN: 9781461422051

SPRINGERBRIEFS IN STEM CELLS INDUCED PLURIPOT...

Induced Pluripotent Stem (iPS) cells are mature cells that have been genetically reprogrammed
so that they return to their embryonic state. It is not yet known if iPS stem cells and
embryonic stem cells differ significantly. Today many fundamental belief systems in biology are
shifting towards accepting that mature body cells can be reverted to an embryonic state without
the help of eggs or embryos. With their changed identities  iPS cells are then ready to serve
as new tools for research in the fields of disease pathogenesis  drug discovery  oncology  and
cell transplantation. One example of this would be using iPS from a patient's mature cells to
repair damaged tissue  it is thought that there would be very low incidence of rejection of the
'new' tissue in these cases. For the last four years  this therapeutic promise has been studied
by hundreds of researchers worldwide in an effort to understand the ability of these cells to
reverse their biological clocks.

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