?Leishmania-related illnesses remain among the world's deadliest neglected tropical diseases
affecting approximately 12 million people in 88 countries. The mortality rate is substantial
contributing to nearly two million disability-adjusted life years. As more is understood about
this parasite and its effects work toward prevention control and treatment continues apace.
Leishmania and Leishmaniasis will address the parasite and its attendant disease which
manifests in three syndromes: Visceral (VL) Cutaneous (CL) and Mucocutaneous Leishmaniasis
(ML). The morphology and life cycles of the various species will be among the topics addressed
in Part One. Part Two will focus on immunology including host-immune response to Leishmania
infection cross-immunity between the different species and adoptive transfer of immunity.
Parts Three and Four will address how Leishmania invade and survive the clinical features of
the disease and its diagnosis. Drugs vaccines and treatment will be thoroughly explored
including experimental models of therapeutics. Leishmania and Leishmaniasis will provide a
thorough examination of a parasite the illnesses it causes and the misery it continues to
visit upon large segments of the population.?
