Caroline Hébert and a panel of key experimentalists and clinical investigators comprehensively
review the state-of-the-art in the chemokine field ranging from the effects of chemokines and
their receptors in retroviral infections to their role in inflammation angiogenesis
angiostasis and tumor cell biology. The book examines in detail fifteen recently identified
chemokines and elucidates the role of chemokine function in vivo from animal experiments.
Animal models are also used to explore how chemokines operate in a variety of chronic and acute
inflammatory diseases and in noninflammatory processes. A detailed review of the emerging role
of chemokines in viral biology is also presented with emphasis on HIV biology and novel
therapeutic possibilities. Chemokines in Disease: Biology and Clinical Research summarizes the
rapidly expanding knowledge of a dazzling array of chemokines and provides fresh insights into
the development of powerful new drugs for treating a wide spectrum of diseases.
