Providing a selection of the key techniques that are used in characterizing cerebral
angiogenesis Cerebral Angiogenesis: Methods and Protocols aims to define the cellular and
molecular mechanisms underlying this important process. Divided into six parts this detailed
volume examines cerebral angiogenesis occurring in different scenarios a variety of different
models in which cerebral angiogenesis can be studied methods to characterize and quantify
angiogenic events as well as several different approaches to measure changes in cerebral blood
flow different approaches to investigate the role of specific candidate genes in cerebral
angiogenesis methods of therapeutically manipulating cerebral angiogenesis by gene delivery
and finally important approaches to examine cerebral angiogenic mechanisms in vitro. Written in
the highly successful Methods in Molecular Biology series format chapters include
introductions to their specific topics lists of the necessary materials and reagents
step-by-step readily reproducible laboratory protocols and tips on troubleshooting and
avoiding known pitfalls. Comprehensive and decidedly practical Cerebral Angiogenesis: Methods
and Protocols should be a vital resource for all researchers both those new to this field as
well as those looking to use more specialized and sophisticated techniques to examine blood
vessel growth in the brain.
