RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent
advances in siRNA design delivery targeting and methods to minimize siRNA's unwanted effects.
Preclinical and clinical use of synthetic siRNAs the roles of miRNAs in cancer and the promise
of extracellular miRNAs for diagnosis are also covered in this meticulous collection along
with novel methods for identifying endogenous siRNAs and the annotation of small RNA
transcriptomes. Written for the highly successful Methods in Molecular Biology series chapters
include the kind of detail and key implementation advice that ensures successful results in the
laboratory.Comprehensive and cutting-edge RNA Interference: Challenges and Therapeutic
Opportunities will aid researchers clinicians teachers and biotechnologists interested in the
power of RNA-based therapies.