EAN: 9781493917136

GLYCOSAMINOGLYCANS GEBUNDEN

Glycosaminoglycans: Chemistry and Biology emphasizes several areas of glycosaminoglycan
research especially analysis and application of GAGs using a variety of approaches. Chapters
focus on chemical and enzymatic synthesis of GAGs for therapeutic purposes  biophysical and
biochemical methods for studying GAG-protein interactions  molecular approaches for modulating
and defining GAG biosynthesis  informatics approaches for deciphering GAG code  computational
approaches for establishing specific and or non-specific interactions and genetic and
biochemical tools for manipulating visualizing glycosaminoglycan expression and studying their
functions in a variety of model organisms. Written in the highly successful Methods in
Molecular Biology series format  chapters include introductions to their respective topics 
lists of the necessary materials and reagents  step-by-step  readily reproducible laboratory
protocols and key tips on troubleshooting and avoiding known pitfalls. Authoritative and
practical  Glycosaminoglycans: Chemistry and Biology serves as a valuable manual for cutting
edge methodologies and practical tips to overcome any obstacles with experimentation pertaining
to chemistry and biology of glycosaminoglycans.

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