The release of the complete version of the human genome sequence in 2003 has paved the way for
defining gene function and genetic background for phenotypic variation in humans and allowed us
to study the aging process in a new light. This new volume results from that research and
focuses on the genetic and epigenetic process of aging. While the interpretation of the genome
data is still in its initial stages this new volume looks at the evolving understanding of
molecular mechanisms involved in cellular processes gene function associated with complex
traits epigenetic components involve in gene control and the creation of hypothesis-free
genome-wide approaches. Longevity Genes: A Blueprint for Aging explores the genetic and genomic
elements that can maintain a long life such as DNA damage mechanisms epigenetics and the way
we can use this knowledge to generate customized treatments. It touches on some of the
multidisciplinary approaches as well as genomic-wide association technology used to analyze
complex traits. This book describes the hunt for genes affecting complex traits using a high
throughput technology with adequate consideration for the selection of an appropriate
population applications of statistical genetics and computational biology and most
importantly considering phenotype-genotype association studies. Longevity Genes provides
coverage of not only established aspects of genetics and aging but also new approaches and
perceptions in this important area of research.
