?????????? This volume presents aspects of the inflammatory tumor microenvironment (TME) and
its many roles in tumor progression and metastasis including creation of a hypoxic environment
increased angiogenesis and invasion changes in expression of microRNAs (miRNAs) and an
increase in a stem cell phenotype. The volume also covers the mechanisms of inflammatory
mediators. Chronic overexpression of inflammatory mediators in the TME as seen in smokers and
patients with non-small cell lung cancer (NSCLC) can also lead to increased tumor initiation
progression invasion and metastasis. The volume will provide a comprehensive perspective of
the latest findings and summaries of progress made regarding inflammation and its connection to
lung cancer.
