This volume presents state-of-the-art methods for reliable detection of epigenetic changes in
the nervous system. Epigenetic Methods in Neuroscience Research guides readers through methods
for the analyses of chromatin remodeling transposable elements non-coding RNAs such as
miRNAs and circadian oscillations including: analysis of DNA methylation in neuronal and
glial cells or small tissue samples sensitive method for quantification of alternative
methylated forms of cytosines by liquid chromatography mass spectrometry affinity-based
detection of modified cytosines by immunohistochemistry or methylated DNA immunoprecipitation
chromatin immunoprecipitation or ChIP miRNA high-throughput profiling and the in situ
detection of miRNA subtle expression in the brain analysis of genes with alternative 3¿UTRs
and the cite-specific delivery of chromatin-modifying drugs. Written in the popular
Neuromethods series style chapters include the kind of detail and key advice from the
specialists needed to get successful results in your own laboratory. Concise and easy-to-use
Epigenetic Methods in Neuroscience Research provides multidisciplinary epigenetic approach to
study genome and neural plasticity that will help the reader to successfully address the
challenges associated with neurodevelopmental psychiatric and neurodegenerative disorders.
