This fourth edition reflects the most recent technical advances in DNA-protein interaction
research. With fully updated chapters that describe techniques proven by their continuous value
the volume also many new chapters have been added that mostly deal with larger-scale
experiments reflecting recent advances in big biology combining to offer a very useful
compendium of protocols allowing readers to delve into the intricacies of protein-DNA
interaction at levels ranging from the very small (as in the case of single-molecule FRET) to
the very complex (as with circular chromatin conformation capture or 4C). Written for the
highly successful Methods in Molecular Biology series chapters include introductions to their
respective topics lists of the necessary materials and reagents step-by-step readily
reproducible laboratory protocols and tips on troubleshooting and avoiding known
pitfalls.Authoritative and up-to-date DNA-Protein Interactions: Principles and Protocols
Fourth Edition will aid researchers in continuing the incredible progress made in this vital
area of study.
