In this book leading figures in the field of Developmental Origins of Health and Disease
provide up-to-date information from human clinical trials cohorts and animal physiology
experiments to reveal the interdependence between parental obesity and health of the offspring.
Obesity of the mother and father produces obesity in their offspring so we are caught up in an
intergenerational cycle which means that even our children's future health is in peril. This
book gives a timely and much-needed synthesis of the mechanisms potential targets of future
interventions and the challenges that need to be overcome in order to break the
intergenerational cycle of obesity. This has profound implications for the way in which
scientific clinical and health policy activities are to be directed in order to combat the
so-called epidemic of obesity as well as diabetes cancer and cardiovascular disease. The book
will be of interest to students clinicians researchers and health policymakers who are either
seeking an introduction to the area of Developmental Origins of Health and Disease or have a
specific interest in the pathogenesis of obesity.
