Given the variety of studies and data that have suggested the existence of heterogeneous
populations or subpopulations of stem cells this detailed volume examines different aspects of
stem cell heterogeneity. This goes against the long-held tenet that stem cells defined by
their capacity for self-renewal and lineage development comprised a homogenous population
thus providing the reader with a new avenue of exploration into the complex world of stem cell
study. Written for the highly successful Methods in Molecular Biology series chapters include
introductions to their respective topics lists of the necessary materials and reagents
step-by-step readily reproducible laboratory protocols and tips on troubleshooting and
avoiding known pitfalls. Authoritative and practical Stem Cell Heterogeneity: Methods and
Protocols serves as an ideal guide for investigators exploring this important area of research.
