This fully updated and revised second edition address specifically some of the significant
advances made in our understanding of the pathophysiology of penile cancer including discussion
of the suspected role of the human papilloma virus in penile carcinogenesis. Similarly the
molecular pathways implicated in precancerous and penile cancer will be discussed as these are
the present targets of novel therapeutic approaches to this disease. The text details the
recent national and international diagnostic and treatment guidelines that have been developed
by both the National Comprehensive Cancer Network© and the European Urological Association
establishing evidence based standards upon which the care of penile cancer should be based. The
text also covers significant advances made in the diagnostic and therapeutic approach to both
primary tumors and inguinal nodal metastases resulting from penile cancer such as penile
sparing surgery and minimally invasive inguinal lymph node surgery. The text will similarly
highlights the improvement in cancer specific outcome in the management of loco-regionally
advanced (N2 3) penile cancer managed by upfront systemic chemotherapy followed by
consolidative surgery in appropriately selected patients based on recent prospective phase II
data. It also covers the role of radiotherapy in the management of penile cancer for both
primary tumors and or at sites of regional or distant metastases. Finally some of the novel
systemic approaches being devised in the management of advanced penile cancer along with some
upcoming international trials soon to be opened which likely will re-define the present
therapeutic approaches to penile cancer are discussed. The Second Edition of Penile Cancer:
Diagnosis and Treatment will constitute a comprehensive review of the above mentioned subjects
in addition to a few select topics of high clinical relevance with the readership
predominantly consisting of urologists medical and surgical oncologists and other healthcare
professionals.
