This second edition book explores breakthrough technologies in the field of drug target
identification and validation. The volume emphasizes particularly revolutionary technologies
such as CRISPR-related screening ¿big data ¿ and in silico approaches as well as in vivo
applications of CRISPR and best uses of animal models in drug development. Written for the
highly successful Methods in Molecular Biology series chapters include introductions to their
respective topics lists of the necessary materials and reagents step-by-step readily
reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.
Fully updated and authoritative Target Identification and Validation in Drug Discovery:
Methods and Protocols Second Edition is an ideal guide for molecular and cellular biologists
pharmacologists pathologists bioinformaticians clinical researchers or investigators as
well as experts in other fields that need a quick overview of these state-of-the-art
technologies.
