This second edition volume expands on the previous edition with an update on the latest
developments in the field and new techniques used to study secondary and supersecondary
structures (SSS) in proteins. Chapters in this book discuss topics such as sequence and
structural features of different SSS elements software used for the automatic annotation of
secondary structure elements in proteins the new developments in secondary and SSS prediction
and the modern approaches for energy landscape calculation protein misfolding and amyloid
structural formation analysis of 'transformer proteins' discovery of the structure of the
hydrophobic nucleus and discussions of the main principles of protein structures formation.
The contributing authors of the volume are the eminent experts in the field of protein research
and bioinformatics. Written in the highly successful Methods in Molecular Biology series format
chapters include introductions to their respective topics lists of the necessary materials and
reagents step-by-step readily reproducible laboratory protocols and tips on troubleshooting
and avoiding known pitfalls.Cutting-edge and authoritative Protein Supersecondary Structures:
Methods and Protocols Second Edition is a valuable resource for researchers who are interested
in learning more about the relationship between amino acids sequences and protein structures
the evolution of proteins and the dynamics of protein formation.