World-renowned experts share the latest updates in translational research as well as surgical
and nonsurgical strategies for treating spinal cord injury Spinal cord injury (SCI) is a
devastating clinically challenging injury leading to varying degrees of neurological function
impairment and paralysis. Underlying biological mechanisms either inhibit or promote new growth
in the spinal cord. Researchers have been making important discoveries about how neurons and
their axons grow in the central nervous system and why they fail to regenerate after SCI.
Although progress has been steady there remains an urgent need to address issues in acute
management such as early decompression and the use of biologics as well as potential solutions
for regeneration. Written by renowned experts in the ever-evolving field of SCI research and
clinical practice the 7th volume in the AOSpine Masters series is a state-of-the-art
compendium on the latest in SCI diagnosis spine surgery interventions and long-term
management. Each chapter contains pearls from leading spine specialists gleaned from the
research laboratory and years of hands-on experience treating SCI patients in the emergency
setting and long term. Key Features: - Pathobiology assessment and diagnostic considerations
- The use of biomarkers as predictors of functional recovery - Surgical and nonsurgical
interventions for traumatic SCI - The role of neural stem cells and biologics in spinal cord
repair - Functional and epidural stimulation and brain-computer interfaces The AOSpine Masters
series a copublication of Thieme and the AOSpine Foundation addresses current clinical issues
featuring international masters sharing their expertise in the core areas in the field. The
goal of the series is to contribute to an evolving dynamic model of evidence-based approach to
spine care. This essential textbook delivers invaluable insights to spine surgeons spinal cord
injury clinicians and researchers and trainees from translational researchers to experienced
researchers and clinicians experienced in the operative and non-operative management of spinal
cord injury.
