Pancreatic ductal adenocarcinoma is the fifth leading cause of cancer death in the USA.
Pancreatic cancer develops as a result of the accumulation of genetic and epigenetic
alterations in cancer-causing genes such as oncogenes and tumor-suppressor genes. The second
edition of Pancreatic Cancer: Methods and Protocols provides a broad range of protocols for
molecular cellular pathological and statistical analyses of sporadic and familial pancreatic
cancer. It covers topics from in-vitro cell cultures to in-vivo mouse models DNA to protein
manipulation and genetic and epigenetic analyses to treatment development. Written in the
highly successful Methods in Molecular Biology¿ series format chapters include introductions
to their respective topics lists of the necessary materials and reagents step-by-step
readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known
pitfalls. Authoritative and practical written by highly renowned investigators with expertise
in pancreatic cancer Pancreatic Cancer: Methods and Protocols Second Edition is an invaluable
source of proven protocols to those who are interested in joining the fight against pancreatic
cancer.
