The purpose of this project is to educate practitioners of liver-directed oncologic therapies
including surgeons and radiologists on the theoretical advantages and clinical implications
for utilizing venous embolization techniques including portal vein and hepatic vein
embolization. Given the enormous interest in these procedures and the evidence that they are
needed this book will further the understanding of those already using these procedures will
enlighten those eager to begin their utilization and stimulate future clinical and basic
research in the fascinating area of liver regeneration physiology. At present there is no
single resource on this topic such that the experiences of practitioners vary widely from
institution to institution. In essence a focused textbook would bring together many points of
view and may help to standardize the many methodologies and approaches that will be presented.
The leading experts from around the world will contribute up-to-date chapters on portal vein
embolization and hepatic vein embolization. Topics that will be covered include pertinent
vascular (microscopic and macroscopic) and surgical anatomy liver regeneration (including the
atrophy-hypertrophy complex) historical perspectives of major hepatic resection various
hepatobiliary surgical procedures factors affecting hypertrophy pathophysiology of
embolization and resection embolization techniques (including approaches and embolic agents)
the indications for embolization and resection (including pre-operative volumetric and
functional assessment and post-embolization follow-up) potential complications outcomes data
for different diseases recently advocated strategies (including definitive treatment of
hepatocellular carcinoma using portal vein embolization after transcatheter arterial
chemoembolization) and future perspectives.
