Handbook of Treatment-resistant Schizophrenia is a concise review of treatment-resistant
schizophrenia's definition measurement tools adherence issues substance abuse optimal
dosing clinician-patient relationships and current management approaches. The book was
originally commissioned with the intention of creating a comprehensive text focusing on
treatment-resistant schizophrenia and its management. The book explores many aspects of the
background and practice- and research-based evidence for treating this complex subset of
schizophrenia including psychopharmacological somatic and nonpharmacological treatment
approaches. While exploring the various therapies for treatment-resistant schizophrenia Dr
Citrome also emphasizes the importance of building strong and trusting relationships between
patients and their clinicians so the clinician can best manage their patient's adherence and
overall treatment.