This book addresses neuroblastoma a type of embryonic tumor derived from neural crest cells
and one of the most frequent extra-cranial solid tumors in children. However the term also
describes a heterogeneous group of tumors the prognosis of which can differ greatly according
to age stage and biology. Some forms undergo spontaneous regression and some are cured by
surgery alone or after chemo-reduction while others exhibit extremely aggressive behavior.
Their successful treatment is one of the best examples of tailored medicine which involves
close collaboration between pediatric surgeons pediatric oncologists radiologists nuclear
medicine specialists biologists oncogeneticists and radiotherapists. The book pursues a
unique approach as it combines most essential insights from all of these fields together with
key information regarding epidemiology physiopathology and palliative care. The respective
chapters were written by the leading international experts on neuroblastoma and present the
latest advances in terms of research surgical approaches and medical treatments. The book
offers an invaluable resource to all pediatric surgeons pediatricians oncologists students
researchers and all others involved in neuroblastoma management who want to benefit from their
colleagues¿ expertise.
