This textbook teaches bioengineers critical concepts about protein three dimensional structures
how proteins fold and how the folding affects the functioning of the protein. Protein folding
has profound effects on the discovery of biopharmaceutical drugs (especially the transport of
immunological compounds to their site of action) as well as on tissue engineering. Dr. Dods
covers topics in easily understood terms through the use of glossaries heading each chapter and
footnotes and summaries at the end of each chapter. The chapters cover disordered proteins and
large sequences of disorder that exists within proteins secondary structure (a-helix and
ß-pleated structure) tertiary and quaternary structure post-translational changes
proteopathies bioengineering approaches used to study protein folding and computer software
for protein folding. For each of these topics the elements of biomolecular imaging cellular
and tissue engineering and health care systems engineering are built. Molecular engineering
concepts such as site-directed mutagenesis are addressed. For reinforcement of the concepts
presented in this text activities and problems (Queries) are included in the chapter.
