This book reviews successes and (remaining) challenges in vaccine development for the selected
Neglected Tropical Diseases (NTD) of Leprosy Leishmaniasis Meliodoisis and Tuberculosis
which are a continuous burden for millions of people in affected areas worldwide. Written by
frontline researchers the volume deep-dives into different vaccine strategies provides
biotechnological background information and also tackles animal models in NTD therapeutics
research. By bringing together state-of-the-art expert knowledge the book contributes to the
aim of ultimately ending the epidemics of neglected tropical diseases complying with UN
Sustainable Development Goal 3 Health and Well-Being.The volume highlights the activities of
the research network VALIDATE (VAccine deveLopment for complex Intracellular neglecteD
pAThogEns) funded by the Medical Research Council in the UK. The four NTDs discussed in the
book were selected as these are in the focus of VALIDATE's research. The book targets
scientists and clinicians working on NTDs as well as all readers with a background in
biomedicine and interest in vaccine development. This is an open access book.