Conventional methods of detecting disease remission in cancers such as leukemia rely on
microscopic analysis of tissue samples. Measurable (or minimal) residual disease (MRD)
describes the presence of disease beyond the levels of sensitivity afforded by microscopy. Fast
Facts: Measurable Residual Disease describes what is meant by MRD the opportunities and
challenges afforded by its identification and the advantages and disadvantages of the methods
used for its detection. Specific examples are given to illustrate the implications of detecting
MRD in different disease scenarios with emphasis on acute myeloid and lymphoblastic leukemias.
With the recognition and monitoring of MRD likely to play an increasingly important role in
disease prognosis and subsequent treatment direction this accessible resource is ideal for any
healthcare professional wanting to know more about this exciting and fast-moving area. Table of
Contents: - What is measurable residual disease? - How isMRD measured? - What is the
significance of MRD?
