Fast Facts Chronic Lymphocytic Leukemia - Toby A Eyre Parag Jasani Lindsey E Roeker Kartoniert (TB)

Chronic lymphocytic leukemia (CLL) is the most diagnosed leukemia in the Western world accounting for approximately 25% of all new leukemia diagnoses. In recent years remarkable progress has been made in our understanding of both the pathophysiology and genetics of CLL. While the disease generally affects older adults and initially follows an indolent course cytogenetic and molecular profiling have helped to predict clinical outcomes. Greater prognostication alongside the development of an increasing armamentarium of novel targeted therapies has enabled us to provide more personalized man agement options for patients. 'Fast Facts: Chronic Lymphocytic Leukemia' covers the epidemiology etiology diagnosis and staging of the disease and the molecular and genetic aspects that underpin treatment and prognosis. It provides a concise overview of treatment options in both the front-line and relapsed refractory settings with particular focus on the novel targeted agents that have overcome many adverse prognostic factors improving overall survival. Table of Contents: -Epidemiology and etiology -Molecular biology and genetics -Diagnosis staging and prognosis -Management -Research directions