This monograph summarizes the large amount of experimental data accumulated during many years
of studying the functions of the blood system and its regulatory mechanisms under the action of
diverse morbific factors within the models of pathological processes (e.g. immobilization
stress blood loss inflammation cytostatic and radiation myelosuppressions experimental
encephalopathies neuroses and spontaneous leucosis). These data are is analyzed with the
understanding that hematopoietic tissue is an integrated system that can react to the
challenges of both the internal and external environments. This analysis helped develop the
theory of hematopoiesis control describing the regularities in the work of basic subdivisions
of the hematopoietic tissue under normal and pathological conditions as well as the
performance and interaction of the local and long-ranged control systems. The monograph is
recommended for Physiologists Pathophysiologists Hematologists Oncologists Pharmacologists
and other professionals.
