Adenosine A2A receptor antagonists have shown great promise in the treatment of Parkinson's
Disease and alleviation of symptoms. This book addresses various aspects of this class of drugs
from their chemical development to their clinical use. Among the many insightful chapters
contained in this book there are three unique reviews that have not previously been published
in any format: (1) a history of istradefylline the first A2A antagonist approved for treatment
of Parkinson's Disease (2) an overview of neuroimaging studies in human death and disease and
(3) a study of urate as a possible biomarker and neuroprotectant.
