In this unique overview of the Hsp60 chaperonin Peter Bross addresses molecular biologists
medical research scientists and individuals interested in molecular or general biology. First
Bross discusses the basics of the Hsp60 chaperonin in terms of its structure and the molecular
mechanisms determining its function. Second the author highlights the multiple roles of Hsp60
for cellular systems and regulatory pathways especially in connection with neurodegenerative
diseases caused by Hsp60 deficiency. Finally the author highlights controversial observations
suggesting additional non-standard functions of Hsp60 in and outside mitochondria as well as
possible gaps in our understanding of the chaperonin. This volume serves as a snapshot suitable
for experienced researcher working in fields related to molecular chaperones yet still
accessible to researchers entering the field.
