This book constitutes the thoroughly refereedpost-conference proceedings of the 10th
International Conference on Large-ScaleScientific Computations LSSC 2015 held in Sozopol
Bulgaria in June 2015.The 49 revised full papers presented were carefullyreviewed and selected
from 64 submissions. The general theme for LSSC 2015 wasLarge-Scale Scientific Computing with a
particular focus on the organizedspecial sessions: enabling exascale computation control and
uncertain systems computational microelectronics - from monte carlo to deterministic approaches
numerical methods for multiphysics problems large-scale models: numericalmethods parallel
computations and applications mathematical modeling andanalysis of PDEs describing physical
problems a posteriori error control anditerative methods for maxwell type problems efficient
algorithms for hybridHPC systems multilevel methods on graphs and applications of
metaheuristicsto large-scale problems.