This book constitutes the thoroughly refereedpost-workshop proceedings of the Second
International Workshop on HybridSystems Biology HSB 2013 held as part of the ECAL 2013 event
in Taormina Italy in September 2013 and the Third International Workshop on HybridSystems
Biology HSB 2014 held as part of CAV 2014 in Vienna Austria inJuly 2014. This volume
presents 8 full papers together with 2invited tutorials surveys from 21 submissions. The HSB
2013 workshop aims at collecting scientistsworking in the area of hybrid modeling applied to
systems biology in order todiscuss about current achieved goals current challenges and future
possibledevelopments. The scope of the HSB 2014 workshop is the general areaof dynamical models
in biology with an emphasis on hybrid approaches which arenot restricted to a narrow class of
mathematical models and which takeadvantage of techniques developed separately in different
sub-fields.
