This book discusses the ways in which mathematical computational and modelling methods can be
used to help understand the dynamics of intracellular calcium. The concentration of free
intracellular calcium is vital for controlling a wide range of cellular processes and is thus
of great physiological importance. However because of the complex ways in which the calcium
concentration varies it is also of great mathematical interest.This book presents the general
modelling theory as well as a large number of specific case examples to show how mathematical
modelling can interact with experimental approaches in an interdisciplinary and multifaceted
approach to the study of an important physiological control mechanism.Geneviève Dupont is FNRS
Research Director at the Unit of Theoretical Chronobiology of the Université Libre de Bruxelles
Martin Falcke is head of the Mathematical Cell Physiology group at the Max Delbrück Center for
Molecular Medicine Berlin Vivien Kirk is an Associate Professor in the Department of
Mathematics at the University of Auckland New Zealand James Sneyd is a Professor in the
Department of Mathematics at The University of Auckland New Zealand.
