¿ Hepatocellular carcinoma (HCC) used to be regarded as a rare disease. However the increasing
numbers of chronic HCC carriers in the U.S. and subsequent increased incidences of HCC seen in
most large medical centers means that it is no longer an uncommon disease for
gastroenterologists or oncologists to encounter and its incidence and epidemiology are
changing. During this exciting time in the field of HCC basic science and clinical management
many changes are simultaneously occurring at multiple levels of our understanding and
management of the disease. Suddenly there are several new choices of therapy to offer
patients. Hepatocellular Carcinoma 3rd edition addresses this fast-changing disease and gives
the reader a clearer understanding of the many mechanisms involved in carcinogenesis of the
liver. This comprehensive and detailed review of how to diagnose and treat hepatocellular
carcinoma is written by international leaders in the field covering both clinical treatment
choices and the basic science underlying HCC development. Updated and enhanced from the last
edition in 2009 Hepatocellular Carcinoma 3rd edition features 12 new chapters including
discussion of molecular markers molecular hepatocarcinogenesis microenvironment
heterogeneity the new and exciting contributions of immunotherapy and updates on the major
effective hepatitis therapies that will transform HCC incidence and perhaps also the therapy.
This cutting-edge text is a vital resource and must-have for today¿s hepatologists and medical
and surgical oncologists. This is a well written text and should be a good reference book for
those who see patients with HCC.. - Practical Gastroenterology ...a useful tool for both
physicians and surgeons with a specific interest in the management of patients with HCC. -
Digestive and Liver Disease