This book is a comprehensive understanding of the evolution of pre-malignant disease
emphasizing common themes in the field including stem cell biology and histologic modes of
cancer progression between the distal esophagus and stomach. Its sixteen chapters discuss
metaplastic tissue change in the upper GI clonalexpansion of early neoplasia stem cell
dynamics in experimental models pathology of early esophageal squamous cell carcinoma
therapeutic modalities for esophageal squamous cell carcinoma pathology of Barrett's esophagus
screening early detection and novel diagnostic tools for Barrett's esophagus clonal evolution
of Barrett's esophagus endoscopic therapeutic modalities of early esophageal cancer pathology
of early gastric cancer and experimental models for gastric cancer. Stem Cells Pre-neoplasia
and Early Cancer of the Upper Gastrointestinal Tract is an integrative text on both the current
state of translational research on every cancer development of the upper gastrointestinal tract
as well as on novel clinical diagnostic and therapeutic modalities. It highlights a rapidly
growing field within cancer research and is essential reading for oncologists biochemists and
advanced graduate students alike. Springer's Advances in Experimental Medicine and Biology
series presents multidisciplinary and dynamic findings in the broad fields of experimental
medicine and biology. The wide variety in topics it presents offers readers multiple
perspectives on a variety of disciplines including neuroscience microbiology immunology
biochemistry biomedical engineering and cancer research.
