This book constitutes the thoroughly refereed post-conference proceedings of the 12th
International Meeting on Computational Intelligence Methods for Bioinformatics and
Biostatistics CIBB 2015 held in Naples Italy in September 2015. The 21 revised full papers
presented were carefully reviewed and selected from 24 submissions. They present problems
concerning computational techniques in bioinformatics systems biology and medical informatics
discussing cutting edge methodologies and accelerate life science discoveries as well as novel
challenges with an high impact on molecular biology and translational medicine.