This book constitutes the refereed proceedings of the 16th Conference of the Spanish
Association for Artificial Intelligence CAEPIA 2016 held in Salamanca Spain in September
2016. The 47 revised full papers presented were carefully selected from 166 submissions. Apart
from the presentation of technical full papers the scientific program of CAEPIA 2016 included
an App contest a Doctoral Consortium and as a follow-up to the success achieved in previously
CAEPIA editions a special session on outstanding recent papers (Key Works) already published
in renowned journals or forums.