Due to the resultant health consequences and considerable increase in prevalence obesity has
become a major worldwide health problem. Obesity and Lipotoxicity is a comprehensive review of
the recent researches to provide a better understanding of the lipotoxicity-related mechanisms
of obesity and the potential for the development of new treatment strategies. This book
overviews the biochemical pathways leading to obesity-related metabolic disorders that occur
subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at
molecular level including the cellular and molecular aspects of breast cancer resistance to
leptin insulin adiponectin and interconnection between the circadian clock and metabolic
pathways during high-fat feeding. Lipotoxicity and Obesity will be a useful resource for
clinicians and basic science researchers such as biochemists toxicologists immunologists
nutritionists adult and pediatric endocrinologists cardiologists as well as students who are
thought in this field.
