In this Brief Joe Jeffers uncovers the life and works of two-time Nobel Laureate Frederick
Sanger. Following Sanger's early life to retirement Jeffers describes how this celebrated
British biochemist became the first person to determine the amino acid sequence of a protein
for which he was awarded the Nobel Prize in 1958. Highlighting Sanger's remarkable career
Jeffers describes Sanger's later change in research direction to investigate deoxyribonucleic
acids (DNA) work for which Sanger also received the Nobel Prize jointly with Paul Berg and
Walter Gilbert in 1980. Joe Jeffers conducted twelve interviews with Sanger over the period of
1999-2009 and he has also spoken to more than 40 of Sanger's colleagues and family members.
This brief provides a rigorous yet concise view of Sanger on a personal and scientific level
and is suitable for biochemists historians or the interested layperson.
