This book constitutes the thoroughly refereed post-workshop proceedings of the International
Workshop on Brain Lesion as well as the challenges on Brain Tumor Segmentation (BRATS)
Ischemic Stroke Lesion Image Segmentation (ISLES) and the Mild Traumatic Brain Injury Outcome
Prediction (mTOP) held in Athens October 17 2016 in conjunction with the International
Conference on Medical Image Computing and Computer-Assisted Intervention MICCAI 2016. The 26
papers presented in this volume were carefully reviewed. They present the latest advances in
segmentation disease prognosis and other applications to the clinical context.
