This book constitutes the refereed proceedings of the 16th Conference on Artificial
Intelligence in Medicine AIME 2017 held in Vienna Austria in June 2017. The 21 revised full
and 23 short papers presented were carefully reviewed and selected from 113 submissions. The
papers are organized in the following topical sections: ontologies and knowledge representation
Bayesian methods temporal methods natural language processing health care processes and
machine learning and a section with demo papers.