This book describes applications of acridines for the treatment of various neurodegenerative
diseases such as Alzheimer's disease Parkinson's disease and various prion diseases and
discusses the potential of acridines in neuro-regenerative medicine. Using modern data-mining
software it presents structures of acridines with nucleic acids and proteins and compares them
with the native structures. Furthermore the book presents modern methods of acridine synthesis
comparing them with the most useful conventional methods. Acridines interact with both nucleic
acids and proteins and due to their direct interactions with various enzymes they can be
suitable for the treatment of neurodegenerative diseases inflammation immunological disorders
and protozoal diseases. The characteristic spectral properties of acridines can be employed in
labeling proteins nucleic acids lipids and even cells and their compartments. Moreover they
can be applied in photodynamic therapy.
