This book presents expert opinions on a variety of key topics related to the management of
breast cancer with a focus on the implications of recent advances and research findings for
clinical practice. It also explores the controversy regarding mammography screening and reviews
the contribution of new imaging modalities. Considerable attention is paid to developments in
surgical procedures including the potential for the safe and effective use of sentinel lymph
node dissection alone-even in patients with positive nodes-and to the advantages and
contraindications of new radiotherapy techniques. Genetic aspects are discussed in detail
including an assessment of the role of genetic testing and the potential impact of genetic
signatures on breast cancer management. New systemic strategies such as anti-HER2 therapy
endocrine agents and agents to reverse endocrine resistance are considered and the optimal
use of chemotherapy for early-stage and advanced-stage disease is addressed. In closing the
book shares important new insights into lifestyle risk factors risk reduction strategies and
survivor issues including sexual dysfunction and fertility maintenance.
