This practically oriented book provides an up-to-date overview of all significant aspects of
the pathogenesis of sepsis and its management including within the intensive care unit.
Readers will find information on the involvement of the coagulation and endocrine systems
during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention.
International clinical practice guidelines for the management of sepsis are presented and
individual chapters focus on aspects such as fluid resuscitation vasopressor therapy response
to multiorgan failure antimicrobial therapy and adjunctive immunotherapy. The closing section
looks forward to the coming decade discussing novel trial designs sepsis in low- and
middle-income countries and emerging management approaches. The book is international in scope
with contributions from leading experts worldwide. It will be of value to residents and
professionals practitioners in the fields of infectious diseases and internal medicine as well
as to GPs and medical students.
