This book constitutes the proceedings of the 16th International Conference on Practical
Applications of Agents and Multi-Agent Systems PAAMS 2018 held in Toledo Spain in June
2018. The 20 regular and 19 demo papers presented in this volume were carefully reviewed and
selected from 57 submissions. They deal with the application and validation of agent-based
models methods and technologies in a number of key applications areas such as: energy and
security engineering and tools evaluation and ethics negotiation and organisations
personalization and learning simulation applications simulation platforms social networks
and humans. The book also contains two invited talks in full paper length.