This text presents comprehensive review of the recommendations of the Papanicolaou Society of
Cytopathology for reporting results of respiratory cytology specimens along with advances in
diagnostic prognostic and predictive immunohistochemical and molecular techniques which can
be performed on cytology specimens.The majority of the text focuses on the standardized
terminology and nomenclature for respiratory cytology as recommended by the Papanicolaou
Society of Cytopathology. Each of the diagnostic categories are described in depth and formal
definitions for each category are given along with cytologic criteria. Explanatory notes are
given discussing limitations of the category as well as its malignancy risk and
reproducibility. Management recommendations are supplied for each category. Sample reports
documenting the preferred reporting format are also given. Each category is associated with a
reference list establishing the evidence based nature of the categories. An in depth discussion
of ancillary testing is provided including the utilization of microbiologic culture
immunohistochemistry and molecular techniques. Substantial emphasis is placed on molecular
diagnostics necessary for optimization of personalized testing and the appropriate use of
targeted therapies. The text represents a comprehensive resource for the state of the science
of the cytologic diagnosis of respiratory lesions.
